Ethanol Shot to the Heart Saves Man






A cardiologist in England gained international attention when he used an unconventional procedure — a shot of basic alcohol to the heart — to stop an unusual cardio rhythm in an elderly patient.


Dr. Tom Johnson, who carried out the procedure at the Bristol Heart Institute Hospital in Bristol, England, said Ronald Aldom, 77, was doing “fantastically well” after Johnson and his team used pure ethanol to treat Aldom’s rapid heartbeat, a condition called ventricular tachycardia, or VT, about six weeks ago. VT, which starts in the lower two chambers of the heart — the ventricles — can be life-threatening if it goes untreated.






“He’s got a lot of life to live,” Johnson said.


It may seem like a story lifted out of “Pulp Fiction,” but treating VT with ethanol, though rare, is an accepted method that has been used for years. What was noteworthy about Johnson’s procedure was that he had never used ethanol to treat VT before, nor had it ever been done in that part of the United Kingdom.


“[Aldom] was at a point where he felt he had no other option and was kind of facing death,” Johnson said. “While it sounds like a very barbaric treatment, it was a very rewarding one, [but] very high risk.”


Typically, a radio frequency catheter ablation is the treatment choice for someone with VT. A radio frequency catheter is an electrical probe that is threaded into the heart and uses low-voltage electricity to kill the heart tissue around the area causing the arrhythmia. This prevents the tissue from continuing to produce the abnormal rhythm. 




California Man Undergoes ‘Breathing Lung’ Transplant Watch Video



But Johnson said his colleagues had already tried that technique on Aldom, who had also previously endured heart attacks, without success — scar tissue that forms after heart attacks can reject the electrical treatment.


“It was complicated by the fact that [Aldom] had severe damage to his heart already,” Johnson said. “It got to the point where this poor man was like, ‘please shut it off and let me die.’”


Ethanol ablation works in the same way in that it also selectively destroys heart tissue, but it is more commonly used to treat hypertrophic cardiomyopathy, a condition in which the heart muscle is thick or “bulky,” Johnson said. While he had used ethanol to treat hypertrophic cardiomyopathy before, to use it on Aldom was a last resort.


“This guy had no other option, which is why we were able to do something we had never done before,” Johnson said.


The first step, Johnson said, was for him and his team to electronically map the heart to find and isolate the tissue that was causing the abnormal rhythm. Once the problem artery was located, Johnson’s team fed a wire into the vein graph and inflated a balloon to block the artery. Through that balloon, Johnson said they injected the ethanol while the patient was under anesthetic, killing off the problem tissue.


Destroying the tissue creates a controlled, “selective” heart attack, which can be painful, Johnson said, but it allows the heartbeat to return to normal. 


Using ethanol can have risky complications, Johnson said, because not only does it kill tissue, it can also kill some of the electrical function of the heart — Aldom was already using a pace maker. Another risk, Johnson said, was that the balloon could shift, killing more tissue than intended. But his procedure came through successfully.


Dr. Richard Page, the chairman of the department of medicine at the University of Wisconsin School of Medicine and Public Health and a past-president of the Heart Rhythm Society in the United States, agreed that using ethanol to treat VT was “not a routine procedure at all.”


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Monti ‘available to lead Italy’







Italian Prime Minister Mario Monti says he is not siding for now with any party in upcoming elections, but remains available to head a future government.






Mr Monti said he was ready to lead any coalition committed to his reforms.


The caretaker prime minister said he was unable to accept an offer from former Prime Minister Silvio Berlusconi to lead a centrist coalition.


Elections are to be held in February. Mr Monti resigned after Mr Berlusconi’s party withdrew its support.


Mr Monti was nominated as technocratic prime minister in November 2011, after Mr Berlusconi’s centre-right coalition government fell amidst a financial and economic crisis.


Speaking at a news conference in Rome, Mr Monti urged Italian parties not to destroy what he said was his government’s achievement in saving Italy from that crisis.


“That financial emergency has been overcome,” he said. “Italians can once again hold their heads high as citizens of Europe.”


Keeping options open


Asked repeatedly if he was going to run in the 24-25 February election, Mr Monti said he cared more about policies than about the personalities involved in the election.


“I’m not siding with anyone – I’d like parties and social forces to side with ideas,” he said.


But he added: “To the forces that show convinced and credible adherence to the Monti agenda, I would be ready to give my advice, my encouragement and if necessary leadership,” he said.


“I would also be ready to assume one day, if required by circumstances, the responsibilities that would be entrusted to me by the parliament.”


The BBC’s David Willey says Mr Monti, whose possible role in February’s election has been the subject of intense speculation in Italy, is playing his cards close to his chest – whilst keeping his options open.


Mr Monti, 69, is an economist and former EU commissioner who first served as a minister under Mr Berlusconi in 1994.


His government has been praised for its initial reforms and for calming financial markets, though much of its reform agenda has been watered down or blocked.


On Sunday, he appealed to parties to push through further reforms of Italy’s labour market and its institutions.


He also criticised Mr Berlusconi for recently attacking the technocratic government, despite having previously praised it.


“I struggle to follow his line of thought,” Mr Monti said.


Mr Berlusconi, 76, has been mired in a series of sexual and financial scandals.


He made conflicting statements about whether he would remain in politics before launching into his sixth general election campaign.


Current polls suggest the centre-left Democratic Party led by Pier Luigi Bersani would win the most votes in a general election.


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U.N. General Assembly voices concern for Myanmar’s Muslims






UNITED NATIONS (Reuters) – The U.N. General Assembly expressed serious concern on Monday over violence between Rohingya Muslims and Buddhists in Myanmar and called upon its government to address reports of human rights abuses by some authorities.


The 193-nation General Assembly approved by consensus a non-binding resolution, which Myanmar said last month contained a “litany of sweeping allegations, accuracies of which have yet to be verified.”






Outbreaks of violence between ethnic Rakhine Buddhists and the Rohingyas have killed dozens and displaced thousands since June. Rights groups also have accused Myanmar security forces of killing, raping and arresting Rohingyas after the riots. Myanmar said it exercised “maximum restraint” to quell the violence.


The unanimously adopted U.N. resolution “expressing particular concern about the situation of the Rohingya minority in Rakhine state, urges the government to take action to bring about an improvement in their situation and to protect all their human rights, including their right to a nationality.”


At least 800,000 Muslim Rohingyas live in Rakhine State along the western coast of Myanmar, also known as Burma. But Buddhist Rakhines and other Burmese view them as illegal immigrants from neighboring Bangladesh who deserve neither rights nor sympathy.


The resolution adopted on Monday is identical to one approved last month by the General Assembly’s Third Committee, which focuses on human rights. After that vote, Myanmar’s mission to the United Nations said that it accepted the resolution but objected to the Rohingyas being referred to as a minority.


“There has been no such ethnic group as Rohingya among the ethnic groups of Myanmar,” a representative of Myanmar said at the time. “Despite this fact, the right to citizenship for any member or community has been and will never be denied if they are in line with the law of the land.”


(Reporting By Louis Charbonneau; Editing by Paul Simao)


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U.N. General Assembly voices concern for Myanmar’s Muslims






UNITED NATIONS (Reuters) – The U.N. General Assembly expressed serious concern on Monday over violence between Rohingya Muslims and Buddhists in Myanmar and called upon its government to address reports of human rights abuses by some authorities.


The 193-nation General Assembly approved by consensus a non-binding resolution, which Myanmar said last month contained a “litany of sweeping allegations, accuracies of which have yet to be verified.”






Outbreaks of violence between ethnic Rakhine Buddhists and the Rohingyas have killed dozens and displaced thousands since June. Rights groups also have accused Myanmar security forces of killing, raping and arresting Rohingyas after the riots. Myanmar said it exercised “maximum restraint” to quell the violence.


The unanimously adopted U.N. resolution “expressing particular concern about the situation of the Rohingya minority in Rakhine state, urges the government to take action to bring about an improvement in their situation and to protect all their human rights, including their right to a nationality.”


At least 800,000 Muslim Rohingyas live in Rakhine State along the western coast of Myanmar, also known as Burma. But Buddhist Rakhines and other Burmese view them as illegal immigrants from neighboring Bangladesh who deserve neither rights nor sympathy.


The resolution adopted on Monday is identical to one approved last month by the General Assembly’s Third Committee, which focuses on human rights. After that vote, Myanmar’s mission to the United Nations said that it accepted the resolution but objected to the Rohingyas being referred to as a minority.


“There has been no such ethnic group as Rohingya among the ethnic groups of Myanmar,” a representative of Myanmar said at the time. “Despite this fact, the right to citizenship for any member or community has been and will never be denied if they are in line with the law of the land.”


(Reporting By Louis Charbonneau; Editing by Paul Simao)


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8 New Etiquette Rules for Using Gadgets in the Office






As the use of personal technology increases at work, it’s important to observe some new etiquette rules about how we use it. Here are eight of the most important rules to follow at work when it comes to cell phones, email, and other modern technology.


1. Using speaker phone when others can hear you. Playing back your voicemail messages on speaker phone or conducting an entire call on speaker phone is distracting to people trying to work around you. Even if you’re in an office with the door closed, speakerphone noises tend to travel. Don’t value your hands-free convenience over the ability of others to focus on their work.






2. Keeping your cell phone out so you can glance at it during meetings. Glancing down at your phone while you’re supposed to be focused on a meeting signals that you’re bored, not fully engaged, or don’t respect the time of the people you’re meeting with. If you must keep your phone out because you’re expecting an important call or text, explain that at the start of the meeting so that people don’t assume you’re just being rude.


3. Don’t overuse “reply all.” When multiple people are included on an email chain, they don’t all need to see your reply of “thanks” or “will do.” Only use “reply all” if everyone included truly needs to see your response; otherwise, stick with “reply” so your response goes only to the sender and doesn’t clutter multiple in-boxes.


4. Don’t email and phone with the same message; pick one or the other. Nothing is more annoying than starting to read an email, only to have the email’s sender pop his head in your office to repeat the same message.


5. Turn off your cell phone’s ringer if you leave it behind while you’re away from your desk. Ask any office worker, and you’ll hear stories about the annoying guy who leaves his phone behind with his ringer on full-volume while he goes to meetings … leaving his co-workers forced to hear repeated renditions of “Who Let the Dogs Out” or whatever else he’s chosen for his ringtone.


6. Placing calls from a noisy location. If you make a call, ensure you’re somewhere where you and the person you’re speaking with will be able to hear each other–and where you can give your full focus. It’s irritating to get a call from someone who immediately puts you on hold to order coffee because she just reached the front of the line.


7. Keep religious and political messages out of your email signature. Including religious or political messages is likely to offend or at least irritate some of your recipients, and introduces topics that don’t belong in a professional setting. Keep your sign-off neutral and professional.


8. Don’t use your work email as your personal email. In most offices, sending occasional personal emails from your work account is fine, but you should use your personal account for most personal things. If you treat your work email as your default personal account, chances are good that when you leave your job and your inbox and sent folder are full of personal messages, one of your co-workers will be stuck reading through all of them, as they clean out your account for your replacement. In the best case scenario, that’s merely a nuisance for a co-worker –but in the worst case scenario, it could lead to embarrassing revelations.


Alison Green writes the popular Ask a Manager blog, where she dispenses advice on career, job search, and management issues. She’s also the co-author of Managing to Change the World: The Nonprofit Manager’s Guide to Getting Results, and former chief of staff of a successful nonprofit organization, where she oversaw day-to-day staff management, hiring, firing, and employee development.


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FDA warns doctors of counterfeit Botox






WASHINGTON (AP) — Federal regulators have warned more than 350 medical practices that Botox they may have received from a Canadian supplier is unapproved and could be counterfeit or unsafe.


The Food and Drug Administration said in a letter sent last month, a letter released publicly last week, that batches of the wrinkle treatment shipped by suppliers owned by pharmacy Canada Drugs have not been approved by the FDA and that the agency cannot assure their effectiveness or their safety.






The FDA said Canada Drugs was previously tied to shipping unapproved and counterfeit cancer drugs.


The agency warned doctors about buying drugs from sources other than licensed U.S. pharmacies. It is the fifth warning the agency has made this year about foreign suppliers providing unapproved drugs.


In February, the agency warned 19 medical practices that they had received a counterfeit version of the cancer drug Avastin. On three more occasions the FDA issued similar warnings about counterfeit Avastin and Altuzan, another brand name for the same drug. The alerts were also primarily targeted at drugs distributed by Canada Drugs.


A request for comment from the drug distributor was not immediately returned.


Drug shortages increased the financial incentives for some pharmacies to provide counterfeit or illegally imported drugs. The drugs subject to warnings have all been injectable treatments typically distributed through medical practices and not directly to patients.


In October, the FDA ordered operators of about 4,100 websites to immediately stop selling unapproved medications to U.S. consumers. The vast majority of those sites were operated by Canada Drugs. The site was still operating Friday.


Genuine Botox is made by Allergan Inc., based in Irvine, Calif. Avastin is made by Roche Holding AG’s Genentech unit.


___


Online:


The FDA’s warning letter, plus a list of doctors who received it: http://1.usa.gov/R7jKiR


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LSE agrees LCH Clearnet purchase







The London Stock Exchange is to buy a 60% stake in LCH Clearnet, the European clearing house, but for a lower price.






The LSE will pay 366m euros ($ 482m; £300m), about 100m euros below the original offer price.


The lower price reflected new European rules requiring clearing houses to hold more capital, the companies said.


Clearing houses enable the trading of shares between two parties, charging a fee to guarantee the sales should one side default.


By requiring clearing houses to hold more money in reserve, the authorities hope to protect such firms against a major customer hitting a financial crisis.


“Today’s announcement is a success for LSE shareholders,” said Peter Lenardos, analyst at RBC Capital Markets.


“We believe that shareholder approvals will be sought in January and we still expect the transaction to complete in the first quarter of 2013.”


The deal was originally due to be completed by the end of this year. The UK’s Office of Fair Trading approved the acquisition earlier this month.


By taking over LCH, the LSE should be better able to compete with rivals such as NYSE Euronext and Deutsche Börse, which own clearing houses.


Demand for clearing transactions are expected to increase over the next few years as regulators force banks and other parties to channel trades through regulated clearing houses to ensure their risk positions can be better monitored.


BBC News – Business





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New Zealand level series thanks to Guptill century






EAST LONDON, South Africa (Reuters) – A brilliant, unbeaten century from opener Martin Guptill led New Zealand to an eight-wicket victory off the final ball against South Africa in the second T20 international on Sunday.


Chasing 169 for victory in 19 overs at Buffalo Park, Guptill helped erase the memory of Friday’s embarrassing capitulation to 86 all out in Durban with a stunning batting display as the tourists reached their target for the loss of just two wickets to level the series 1-1.






Requiring 39 from the final four overs and 11 off the last, Guptill was on 97 and needing four for victory when Rory Kleinveldt bowled the final delivery – a low full toss which was eased away through extra cover.


Guptill’s unbeaten 101 was just the third T20 international century by a New Zealander, the first two belonging to captain Brendon McCullum who was almost anonymous with 17 from 15 balls during a second-wicket partnership of 73 with Guptill.


The right-handed opener was similarly dominant during an opening stand of 76 with Rob Nicol (25) as he drove the Proteas attack impeccably straight and displayed the skills – and patience – so obviously missing from the New Zealand batsman in Durban.


Captain Faf du Plessis led from the front once again as South Africa posted a competitive 165-5 in 19 overs after losing the toss and being asked to bat first.


Du Plessis paced his innings to perfection on a tricky pitch to reach 63 from 43 balls with eight fours and a six in a match reduced to 19 overs per side following a 52-minute floodlight failure.


The deciding match takes place in Port Elizabeth on Wednesday.


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New Zealand level series thanks to Guptill century






EAST LONDON, South Africa (Reuters) – A brilliant, unbeaten century from opener Martin Guptill led New Zealand to an eight-wicket victory off the final ball against South Africa in the second T20 international on Sunday.


Chasing 169 for victory in 19 overs at Buffalo Park, Guptill helped erase the memory of Friday’s embarrassing capitulation to 86 all out in Durban with a stunning batting display as the tourists reached their target for the loss of just two wickets to level the series 1-1.






Requiring 39 from the final four overs and 11 off the last, Guptill was on 97 and needing four for victory when Rory Kleinveldt bowled the final delivery – a low full toss which was eased away through extra cover.


Guptill’s unbeaten 101 was just the third T20 international century by a New Zealander, the first two belonging to captain Brendon McCullum who was almost anonymous with 17 from 15 balls during a second-wicket partnership of 73 with Guptill.


The right-handed opener was similarly dominant during an opening stand of 76 with Rob Nicol (25) as he drove the Proteas attack impeccably straight and displayed the skills – and patience – so obviously missing from the New Zealand batsman in Durban.


Captain Faf du Plessis led from the front once again as South Africa posted a competitive 165-5 in 19 overs after losing the toss and being asked to bat first.


Du Plessis paced his innings to perfection on a tricky pitch to reach 63 from 43 balls with eight fours and a six in a match reduced to 19 overs per side following a 52-minute floodlight failure.


The deciding match takes place in Port Elizabeth on Wednesday.


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Without an ‘iTV,’ Apple’s growth could shrink to the single digits by 2015






Another analyst believes that Apple is losing its shine. Toni Sacconaghi of Bernstein Research on Thursday trimmed his price target for the company, citing concerns that growth may be slowing. The analyst believes that iPhone sales will remain strong for at least the next two years, however Apple (AAPL) is expected to lose overall market share “if it does not bring out a lower-price device” in the wake of a changing industry. Sacconaghi notes that the iPad should continue to see success in a tablet market that is “a rocket…an absolute juggernaut,” with tablet PC shipments estimated to more than triple over the next five years. It is believed, however, that Apple will likely become a single digit growth company by 2015, unless it releases a new major product such as an HDTV.


[More from BGR: RIM’s biggest problem: It’s still scrambling to catch yesterday’s hottest mobile app]






“That said, it will have a pristine balance sheet, and be generating a mind-boggling $ 49 billion in free cash flow a year after paying its current dividend,” Sacconaghi wrote in a note to investors, according to Forbes. “More importantly, we believe that Apple’s innovation offers significant option value, which is not in our forecast. Three years ago, the iPad did not exist. Today it generates $ 32 billon in annual revenues, and as a standalone business would be the 11th biggest U.S. tech company. Potential ‘options’ for Apple investors include a lower-end iPhone, a television ‘solution,’ a larger iPad or converged device and monetizing advertising, e-commerce and search from its iOS platform (and credit card database) of 435 million users.”


[More from BGR: WhatsApp goes free for iPhone for a limited time]


The analyst kept his Outperform rating on shares of Apple, although he trimmed his price target from $ 800 to $ 750 and lowered his 2013 fiscal year EPS forecast to $ 49.41 per share, from $ 50.57.


This article was originally published by BGR


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